Serum Trace Elements and Their Associations with Breast Cancer Subgroups in Korean Breast Cancer Patients.

ABSTRACT: The relationships between serum levels of trace elements and breast cancer remain relatively unknown. In this study, we investigate serum levels of seven trace elements in Korean breast cancer patients compared to controls without breast cancer. Serum trace element levels were determined using inductively coupled plasma mass spectrometry in Korean breast cancer patients before initiation of breast cancer treatment. Korean females without breast cancer served as a control group. Trace element levels were measured in the discovery cohort (n = 287) and were validated in an independent cohort (n = 142). We further investigated possible associations between trace element levels and the presence of lymph node metastasis, distant metastasis, or triple-negative breast cancer among br

SUBMITTER: Choi R 

PROVIDER: S-EPMC6357144 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature