A genome-wide analysis of coatomer protein (COP) subunits of apicomplexan parasites and their evolutionary relationships.

ABSTRACT:

Background

Protein secretion is an essential process in all eukaryotes including organisms belonging to the phylum Apicomplexa, which includes many intracellular parasites. The apicomplexan parasites possess a specialized collection of secretory organelles that release a number of proteins to facilitate the invasion of host cells and some of these proteins also participate in immune evasion. Like in other eukaryotes, these parasites possess a series of membrane-bound compartments, namely the endoplasmic reticulum (ER), the intermediate compartments (IC) or vesicular tubular clusters (VTS) and Golgi complex through which proteins pass in a sequential and vectorial fashion. Two sets of proteins; COPI and COPII are important for directing the sequential transfer of material between th

SUBMITTER: Kibria KMK 

PROVIDER: S-EPMC6357402 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature