Differential mobility and local variation in infection attack rate.

ABSTRACT: Infectious disease transmission is an inherently spatial process in which a host's home location and their social mixing patterns are important, with the mixing of infectious individuals often different to that of susceptible individuals. Although incidence data for humans have traditionally been aggregated into low-resolution data sets, modern representative surveillance systems such as electronic hospital records generate high volume case data with precise home locations. Here, we use a gridded spatial transmission model of arbitrary resolution to investigate the theoretical relationship between population density, differential population movement and local variability in incidence. We show analytically that a uniform local attack rate is typically only possible for individual pixels in

SUBMITTER: Haw DJ 

PROVIDER: S-EPMC6358099 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature