Differences and similarities between IgG4-related disease with and without dacryoadenitis and sialoadenitis: clinical manifestations and treatment efficacy.

ABSTRACT:

Background

This study aimed to compare the differences and similarities in the clinical manifestations and treatment efficacy of IgG4-related disease (IgG4-RD) in patients with and without dacryoadenitis and sialoadenitis (DS).

Methods

A total of 121 untreated IgG4-RD patients in Peking Union Medical College Hospital were enrolled in this study. The patients were divided into three groups: DS-predominant (group A), non-DS (group B), and DS with other internal organs affected (group C). The patients were followed up for at least 15 months. Baseline and follow-up data were collected. The disease activity was evaluated according to the IgG4-RD responder index.

Results

The mean ± SD age at disease onset was 53.2 ± 14.1 years, and 71.9% of the patients were male. The preva

SUBMITTER: Wang M 

PROVIDER: S-EPMC6359790 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature