Antilisterial efficacy of Lactobacillus brevis MF179529 from cow: an in vivo evidence.

ABSTRACT:

Background

Listeria monocytogenes is an opportunistic foodborne pathogen that causes human Listeriosis and high mortality particularly in immunocompromised individuals. Pregnant women are more prone to L. monocytogenes infection resulting in abortions. In the present study, antilisterial activity of Lactobacillus brevis (LB) MF179529, a probiotic bacterial strain, was investigated in a murine model.

Methods

Initially a pilot study was conducted to determine the dose of L. monocytogenes required to cause symptomatic listeriosis. In the main trial, mice were divided into 4 groups. Group I was kept as negative control, group II was exposed to L. monocytogenes and maintained as positive control. Group III was fed with L. brevis only, while group IV received L. brevis for 3 days

SUBMITTER: Riaz A 

PROVIDER: S-EPMC6359795 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature