Outcomes and practice patterns with hemodiafiltration in Shanghai: a longitudinal cohort study.

ABSTRACT:

Background

Globally, there is increased clinical interest and uptake of hemodiafiltration (HDF) for increased removal of uremic toxins. To date, there has been no epidemiological analysis of HDF in China. We present HDF practice patterns and associated mortality risk in Shanghai.

Methods

This is an observational, prospectively collected, retrospective analysis of 9351 Chinese patients initiating hemodialysis in Shanghai from 2007 to 2014. The primary exposure was hemodialysis sub-modality at inception, classified into hemodiafiltration (HDF) and hemodialysis (HD), with adjustment for concommitant hemoperfusion. The primary outcome was patient mortality. We used Cox proportional hazards regression and Fine and Gray's proportional subhazards regression, with multiple imputatio

SUBMITTER: Zhang W 

PROVIDER: S-EPMC6359843 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature