Relationships between indicators of cardiovascular disease and intensity of oil and natural gas activity in Northeastern Colorado.

ABSTRACT: BACKGROUND:Oil and natural gas (O&G) extraction emits pollutants that are associated with cardiovascular disease, the leading cause of mortality in the United States. OBJECTIVE:We evaluated associations between intensity of O&G activity and cardiovascular disease indicators. METHODS:Between October 2015 and May 2016, we conducted a cross-sectional study of 97 adults living in Northeastern Colorado. For each participant, we collected 1-3 measurements of augmentation index, systolic and diastolic blood pressure (SBP and DBP), and plasma concentrations of interleukin (IL)- 1β, IL-6, IL-8 and tumor necrosis factor alpha (TNF-α). We modelled the intensity of O&G activity by weighting O&G well counts within 16 km of a participant's home by intensity and distance. We used linear models accounting

SUBMITTER: McKenzie LM 

PROVIDER: S-EPMC6360130 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature