Assessment of Cognitive and Motor Skills in Parkinson's Disease by a Robotic Object Hitting Game.

ABSTRACT: Parkinson's disease (PD) patients experience various symptoms including extrapyramidal motor disturbances and cognitive impairments, which cause difficulties in daily life. However, PD patients have rarely been studied under realistic task situations that require high-level interaction of cognitive and motor skills. The aim of this study was to investigate the contribution of cognitive and motor factors to the performance of PD patients under high cognitive and kinematic loads. Twenty-six PD patients and 14 control subjects participated in the study. The PD patients performed a task involving hitting targets and avoiding distractors in levodopa On and Off states. A robotic manipulandum device recorded the numbers of target and distractor hits and hand kinematics, including movement area an

SUBMITTER: Wiratman W 

PROVIDER: S-EPMC6360146 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature