CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species.

ABSTRACT:

Background

Bacteria are prey for many viruses that hijack the bacterial cell in order to propagate, which can result in bacterial cell lysis and death. Bacteria have developed diverse strategies to counteract virus predation, one of which is the clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR associated (Cas) proteins immune defense system. Species within the bacterial family Vibrionaceae are marine organisms that encounter large numbers of phages. Our goal was to determine the significance of CRISPR-Cas systems as a mechanism of defense in this group by investigating their prevalence, phylogenetic distribution, and genome context.

Results

Herein, we describe all the CRISPR-Cas system types and their distribution within the family Vibrionaceae. I

SUBMITTER: McDonald ND 

PROVIDER: S-EPMC6360697 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature