Multimodal intervention improves fatigue and quality of life in subjects with progressive multiple sclerosis: a pilot study.

ABSTRACT:

Background

Fatigue is a disabling symptom of multiple sclerosis (MS) and reduces quality of life. The aim of this study was to investigate the effects of a multimodal intervention, including a modified Paleolithic diet, nutritional supplements, stretching, strengthening exercises with electrical stimulation of trunk and lower limb muscles, and stress management on perceived fatigue and quality of life of persons with progressive MS.

Methods

Twenty subjects with progressive MS and average Expanded Disability Status Scale (EDSS) score of 6.2 (range: 3.5-8.0) participated in the 12-month phase of the study. Assessments were completed at baseline and at 3 months, 6 months, 9 months, and 12 months. Safety analyses were based on monthly side effects questionnaires and blood analys

SUBMITTER: Bisht B 

PROVIDER: S-EPMC6361513 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature