Sedentary Behaviors, TV Viewing Time, and Risk of Young-Onset Colorectal Cancer.

ABSTRACT:

Background

Colorectal cancer (CRC) diagnosed before age 50 years, or young-onset CRC, is increasing globally with undefined etiology. A sedentary lifestyle is an emerging risk factor for CRC after age 50 years, but its role in young-onset CRC is unknown.

Methods

We prospectively evaluated sedentary behaviors, primarily time watching television (TV), and risk of young-onset CRC among 89 278 women in the Nurses' Health Study II ages 25-42 years at recruitment (1991-2011). We used Cox proportional hazards modelling to estimate relative risks (RR) and 95% confidence intervals (CIs). Statistical tests were two-sided.

Results

We documented 118 young-onset CRCs over 1 262 540 person-years. Sedentary TV viewing time was statistically significantly associated with increased ri

SUBMITTER: Nguyen LH 

PROVIDER: S-EPMC6361621 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature