Anatomical and Neurochemical Correlates of Parental Verbal Abuse: A Combined MRS-Diffusion MRI Study.

ABSTRACT: Despite the critical impact of parental dialog on children who remain physically and psychologically dependent, most studies have focused on brain alterations in people exposed to moderate-to-high levels of emotional maltreatment with/without psychopathology. We measured metabolites in the pregenual anterior cingulate cortex (pgACC) acquired with single-voxel proton magnetic resonance spectroscopy and anatomical connectivity assessed with probabilistic tractography in 46 healthy young adults who experienced no-to-low level parental verbal abuse (paVA) during their childhood and adolescence. The partial least square regression (PLSR) model showed that individual variance of perceived paVA was associated with chemical properties and structural connectivity of pregenual anterior cingulate cor

SUBMITTER: Kim D 

PROVIDER: S-EPMC6361791 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature