Estimation of Cardiovascular Relative Pressure Using Virtual Work-Energy.

ABSTRACT: Many cardiovascular diseases lead to local increases in relative pressure, reflecting the higher costs of driving blood flow. The utility of this biomarker for stratifying the severity of disease has thus driven the development of methods to measure these relative pressures. While intravascular catheterisation remains the most direct measure, its invasiveness limits clinical application in many instances. Non-invasive Doppler ultrasound estimates have partially addressed this gap; however only provide relative pressure estimates for a range of constricted cardiovascular conditions. Here we introduce a non-invasive method that enables arbitrary interrogation of relative pressures throughout an imaged vascular structure, leveraging modern phase contrast magnetic resonance imaging, the virtua

SUBMITTER: Marlevi D 

PROVIDER: S-EPMC6362021 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature