Ontology highlight
ABSTRACT:
SUBMITTER: Dumolt JH
PROVIDER: S-EPMC6362455 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Dumolt Jerad H JH Browne Richard W RW Patel Mulchand S MS Rideout Todd C TC
Molecular nutrition & food research 20181126 2
<h4>Scope</h4>The programming of hepatic lipid dysfunction in response to early cholesterol exposure and the influencing effects of postnatal diet is evaluated in apoE<sup>-/-</sup> mice.<h4>Methods and results</h4>In two separate studies, female mice are assigned to a standard chow (S) or a cholesterol-enriched chow (C) diet during gestation and lactation. Male offspring from each dam are weaned on a postnatal S or a hypercaloric western (W) diet resulting in four experimental groups: S-S and C ...[more]