Topical glyceryl trinitrate for the treatment of tendinopathies: a systematic review.

ABSTRACT:

Objective

To produce a best evidence synthesis of the clinical effects of topical glyceryl trinitrate (GTN) in the treatment of tendinopathies.

Design

A systematic review of published randomised controlled trials (RCTs) of the use of GTN in patients with tendinopathy.

Data sources

MEDLINE, Embase, Scopus and CINAHL from database inception to January 2018.

Methods

We examined RCTs comparing the effects of topical GTN with either placebo or other treatments on tendinopathy. Overall quality of each eligible study was determined based on a combined assessment of internal validity, external validity and precision. The level of evidence for each assessed parameter was rated based on the system by van Tulder et al.

Results

A total of 10 eligible RCTs wer

SUBMITTER: Challoumas D 

PROVIDER: S-EPMC6362607 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature