A portable device for studying the effects of fluid flow on degradation properties of biomaterials inside cell incubators.

ABSTRACT: A portable device was designed and constructed for studying the properties of biomaterials in physiologically relevant fluids under controllable flow conditions that closely simulate fluid flow inside the body. The device can fit entirely inside a cell incubator; and, thus, it can be used directly under standard cell culture conditions. An impedance-driven pump was built in the sterile flow loop to control the flow rates of fluids, which made the device small and portable for easy deployment in the incubator. To demonstrate the device functions, magnesium (Mg) as a representative biodegradable material was tested in the flow device for immersion degradation under flow versus static conditions, while the flow module was placed inside a standard cell incubator. The flow rate was controlled a

SUBMITTER: Jiang W 

PROVIDER: S-EPMC6362820 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature