Behavior and sleep disturbance in Smith-Magenis syndrome.

ABSTRACT: PURPOSE OF REVIEW:To provide an update of the most recent studies on Smith-Magenis syndrome (SMS) with a focus on the unique pattern of behavioral and sleep disturbances associated with the condition. RECENT FINDINGS:The recent literature on SMS has focused on the characteristic severe behavioral and sleep disturbances. A better understanding of the underlying pathophysiological mechanisms and common clinical course has helped further characterize SMS, while much is left to be discovered in regard to effective treatment/management. SUMMARY:SMS is a difficult to manage genetic condition defined by pervasive and progressive behavioral and sleep disturbances with a unique pattern that can often be easily discerned from other neurodevelopmental disorders. Common behavioral features include mal

SUBMITTER: Shayota BJ 

PROVIDER: S-EPMC6362978 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature