Role of a serine protease gene (AccSp1) from Apis cerana cerana in abiotic stress responses and innate immunity.

ABSTRACT: Clip-domain serine proteases (Clip-SPs) mediate innate immunity and embryonic development in insects. However, the function of Clip-SPs in Apis cerana cerana is little known. Here, a Clip-SP gene, AccSp1, was identified. AccSp1 was mainly detected in third and sixth day instar larvae, dark-eyed pupae, and adults (1and 30 days post-emergence). In addition, AccSp1 was expressed at its highest level in the venom gland and epidermis than tentacle, abdomen, muscle, honey sac, head, leg, chest, hemolymph, rectum, and midgut. AccSp1 was induced by 4, 24, and 44 °C; H₂O₂; CdCl_2; HgCl₂; and pesticides (paraquat, pyridaben, and methomyl) and was inhibited by UV light and cyhalothrin treatments. When adults that had been pretreated with dsRNA 6 h prior (kno

SUBMITTER: Gao L 

PROVIDER: S-EPMC6363618 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature