Physiologic Analysis and Clinical Performance of the Ventilatory Ratio in Acute Respiratory Distress Syndrome.

ABSTRACT:

Rationale

Pulmonary dead space fraction (Vd/Vt) is an independent predictor of mortality in acute respiratory distress syndrome (ARDS). Yet, it is seldom used in practice. The ventilatory ratio is a simple bedside index that can be calculated using routinely measured respiratory variables and is a measure of impaired ventilation. Ventilatory ratio is defined as [minute ventilation (ml/min) × Pa_CO2 (mm Hg)]/(predicted body weight × 100 × 37.5).

Objectives

To determine the relation of ventilatory ratio with Vd/Vt in ARDS.

Methods

First, in a single-center, prospective observational study of ARDS, we tested the association of Vd/Vt with ventilatory ratio. With in-hospital mortality as the primary outcome and ventilator-free days as the secondary out

SUBMITTER: Sinha P 

PROVIDER: S-EPMC6363976 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature