Association of Continuation of Loop Diuretics at Hemodialysis Initiation with Clinical Outcomes.

ABSTRACT:

Background and objectives

Loop diuretics are commonly used to manage nondialysis-dependent CKD. Despite benefits of augmented urine output, loop diuretics are often discontinued after dialysis initiation. Here, we assessed the association of the early decision to continue loop diuretics at hemodialysis start with clinical outcomes during the first year of dialysis.

Design, setting, participants, & measurements

We considered all patients on in-center hemodialysis at a large dialysis organization (2006-2013) with Medicare Part A and D benefits who had an active supply of a loop diuretic at dialysis initiation (n=11,297). Active therapy was determined on the basis of whether loop diuretic prescription was refilled after dialysis initiation and within 30 days of exhaustio

SUBMITTER: Sibbel S 

PROVIDER: S-EPMC6364527 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature