Effects of microbiota-driven therapy on inflammatory responses in elderly individuals: A systematic review and meta-analysis.

ABSTRACT: Current evidence suggests that age-associated inflammation, a strong risk factor for the health status of elderly individuals, is closely associated with gut microbiota. Previous animal studies have demonstrated a benefit of microbiota-driven therapy in decreasing low-grade chronic inflammation in elderly individuals; however, it remains controversial in clinical studies. Therefore, the present systematic review and meta-analysis were designed to assess the effects of microbiota-driven therapy on inflammatory markers in elderly individuals. PubMed, EMBASE, and the Cochrane Library were searched with no language restrictions from the inception of the database to November 11th, 2018 to identify all existing literature. We calculated pooled standard mean difference (SMD) using fixed effect mo

SUBMITTER: Qu H 

PROVIDER: S-EPMC6364922 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature