Trajectories of childhood BMI and adult diabetes: the Bogalusa Heart Study.

ABSTRACT:

Aims/hypothesis

The aim of this study was to characterise longitudinal profiles of BMI from childhood and to examine the impact of level-independent childhood BMI trajectories on adult type 2 diabetes.

Methods

The longitudinal cohort consisted of 2449 adults (1613 white and 836 black) who had their BMI measured between four and 15 times from childhood (4-19 years) to adulthood (20-51 years) and fasting glucose measured in adulthood. Model-estimated levels and linear slopes of BMI at childhood age points were calculated in 1-year intervals using growth-curve parameters and their first derivatives, respectively.

Results

BMI from childhood to adulthood fit cubic growth curves; linear and non-linear curve parameters differed significantly between race-sex groups. BMI show

SUBMITTER: Zhang T 

PROVIDER: S-EPMC6365010 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature