Ontology highlight
ABSTRACT:
SUBMITTER: Lutsenko S
PROVIDER: S-EPMC6365103 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Current opinion in chemical biology 20100201 2
Copper plays an essential role in normal human physiology. Copper misbalance affects heart development, CNS and liver function, influences lipid metabolism, inflammation, and resistance to chemotherapeutic drugs. Recent studies yielded new information on the structure, function, and regulation of human copper transporters, uncovered unanticipated functions for copper chaperones, and established connections between copper homeostasis and other metabolic pathways. It has become apparent that the c ...[more]