Real-World Evaluation of Patiromer for the Treatment of Hyperkalemia in Hemodialysis Patients.

ABSTRACT:

Introduction

Patiromer is a potassium (K⁺) binding polymer indicated for treating hyperkalemia. Among patients receiving chronic hemodialysis (HD), this study aimed to identify patient characteristics associated with patiromer initiation, describe patiromer utilization, and analyze serum K⁺ pre- and post-patiromer initiation.

Methods

In a retrospective cohort study, using electronic health record data from a large dialysis provider in the United States (study period: December 21, 2015, to December 20, 2016), HD patients were included who had a medication order for patiromer, sodium polystyrene sulfonate (SPS), or laboratory evidence of hyperkalemia (no K⁺ binder [NoKb] cohort). The index date was the first order for patiromer/SPS, or the firs

SUBMITTER: Kovesdy CP 

PROVIDER: S-EPMC6365398 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature