Depressive Symptoms Associate With Race and All-Cause Mortality in Patients With CKD.

ABSTRACT:

Introduction

Depression is common but underrecognized in patients with chronic kidney disease (CKD), especially among racial/ethnic minorities. We examined the association between depressive symptoms and all-cause mortality (including deaths before and after end-stage renal disease [ESRD]) and whether antidepressant use impacts this association, overall, and by race/ethnicity.

Methods

We ascertained whether the presence of depressive symptoms, defined by a Beck Depression Inventory II (BDI) score of >14 at cohort enrollment, was associated with all-cause mortality (before or after ESRD) among study participants of the Chronic Renal Insufficient Cohort (CRIC) overall and by race/ethnicity. Models were adjusted for socioeconomic factors, baseline CKD severity, time-updated com

SUBMITTER: Tuot DS 

PROVIDER: S-EPMC6365404 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature