Treatment of Calciphylaxis in CKD: A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Calciphylaxis is a life-threatening complication of chronic kidney disease (CKD). To inform clinical practice, we performed a systematic review of case reports, case series, and cohort studies to synthesize the available treatment modalities and outcomes of calciphylaxis in patients with CKD.

Methods

Electronic databases were searched for studies that examined the uses of sodium thiosulfate, surgical parathyroidectomy, calcimimetics, hyperbaric oxygen therapy, and bisphosphonates for calciphylaxis in patients with CKD, including end-stage renal disease. For cohort studies, the results were synthesized quantitatively by performing random-effects model meta-analyses.

Results

A total of 147 articles met the inclusion criteria and were included in the systemati

SUBMITTER: Udomkarnjananun S 

PROVIDER: S-EPMC6365410 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature