An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting.

ABSTRACT:

Introduction

Target delineation variability is a significant technical impediment in multi-institutional trials which employ intensity modulated radiotherapy (IMRT), as there is a real potential for clinically meaningful variances that can impact the outcomes in clinical trials. The goal of this study is to determine the variability of target delineation among participants from different institutions as part of Southwest Oncology Group (SWOG) Radiotherapy Committee's multi-institutional in-silico quality assurance study in patients with Pancoast tumors as a "dry run" for trial implementation.

Methods

CT simulation scans were acquired from four patients with Pancoast tumor. Two patients had simulation 4D-CT and FDG-FDG PET-CT while two patients had 3D-CT and FDG-FDG PE

SUBMITTER: Elhalawani H 

PROVIDER: S-EPMC6365802 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature