New-onset non-infectious pulmonary manifestations among patients with systemic lupus erythematosus in Sweden.

ABSTRACT: OBJECTIVE:The objective was to estimate the incidence of lung disease among patients with systemic lupus erythematosus (SLE). METHODS:Using Swedish register data, we identified patients with SLE and pulmonary diagnoses from the National Patient Register through ICD codes. We matched patients with SLE with individuals from the general population. Patients with SLE with a history of pulmonary disease were excluded. Incidence rates (IR) and 95% confidence intervals (CI) were calculated overall and by type of pulmonary disease for incident (2003-2013) and prevalent SLE separately. Hazard ratios (HR) and 95% CI of the association between SLE and pulmonary disease were estimated using adjusted Cox regression models. Sensitivity analyses using a semi-automated approach to quantitative probabilist

SUBMITTER: Forbess LJ 

PROVIDER: S-EPMC6366020 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature