Monitoring Gas Exchange During Hypothermia for Hypoxic-Ischemic Encephalopathy.

ABSTRACT: OBJECTIVES:Therapeutic hypothermia is standard of care in management of moderate/severe hypoxic-ischemic encephalopathy. Persistent pulmonary hypertension of the newborn is associated with hypoxic-ischemic encephalopathy and is exacerbated by hypoxemia and hypercarbia. Gas exchange is assessed by arterial blood gas analysis (with/without correction for body temperature), pulse oximetry, and end-tidal CO2. DESIGN:A retrospective chart review. SETTINGS:Regional perinatal center in Western New York. PATIENTS:Fifty-eight ventilated neonates with indwelling arterial catheter on therapeutic hypothermia. INTERVENTION:None. MEASUREMENT AND MAIN RESULTS:We compared pulse oximetry, PaO2, end-tidal CO2, and PaCO2 during hypothermia and normothermia in neonates with hypoxic-ischemic encephalopathy usi

SUBMITTER: Afzal B 

PROVIDER: S-EPMC6366447 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature