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Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report.

ABSTRACT: Identifying fastidious pathogens in patients with prosthetic joint infection (PJI) by culture is challenging. Metagenomic next-generation sequencing (mNGS) is a novel culture-independent approach that is associated with a higher likelihood for identifying pathogens. We present a case where mNGS was implemented to identify Parvimonas micra, a rarely reported and difficult-to-culture PJI pathogen.

SUBMITTER: Huang Z 

PROVIDER: S-EPMC6367198 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case report.

Huang Zida Z   Zhang Chongjing C   Li Wenbo W   Fang Xinyu X   Wang Qijin Q   Xing Li L   Li Yingzhen Y   Nie Xifang X   Yang Bin B   Zhang Wenming W  

Journal of bone and joint infection 20190129 1

Identifying fastidious pathogens in patients with prosthetic joint infection (PJI) by culture is challenging. Metagenomic next-generation sequencing (mNGS) is a novel culture-independent approach that is associated with a higher likelihood for identifying pathogens. We present a case where mNGS was implemented to identify <i>Parvimonas micra</i>, a rarely reported and difficult-to-culture PJI pathogen. ...[more]

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