Phenotypic Characterization of Non-toxigenic Clostridioides difficile Strains Isolated From Patients in Mexico.

ABSTRACT: Clostridioides difficile is a Gram positive, sporulated, rod-shape, anaerobic pathogen responsible for nosocomial diarrhea and colitis, mainly in antibiotic treated patients. C. difficile produce two toxins responsible for disease, toxin A (TcdA) and toxin B (TcdB), although not all strains produce them. Non-toxigenic C. difficile (NTCD) strains are able to colonize the intestinal mucosa and are often isolated from asymptomatic individuals. NTCD are poorly studied, their evolutionary history has not been elucidated, and their relationship with illness remains controversial. The aim of this work was to analyze the phenotype of NTCD strains isolated from clinical cases in hospitals of México, and whether NTCD strains present characteristics that differentiate them from t

SUBMITTER: Camorlinga M 

PROVIDER: S-EPMC6367242 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature