The Long Pentraxin PTX3 Is of Major Importance Among Acute Phase Proteins in Chickens.

ABSTRACT: The expression level of acute phase proteins (APPs) mirrors the health status of an individual. In human medicine, C-reactive protein (CRP), and other members of the pentraxin family are of significant relevance for assessing disease severity and prognosis. In chickens, however, which represent the most common livestock species around the world, no such marker has yet gained general acceptance. The aim of this study was therefore, to characterize chicken pentraxin 3 (chPTX3) and to evaluate its applicability as a general marker for inflammatory conditions. The mammalian and chicken PTX3 proteins were predicted to be similar in sequence, domain organization and polymeric structure. Nevertheless, some characteristics like certain sequence sections, which have varied during the evolution of m

SUBMITTER: Burkhardt NB 

PROVIDER: S-EPMC6367253 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature