Which quadrant is less painful for intravitreal injection? A prospective study.

ABSTRACT:

Purpose

To evaluate the relationship between injection site and pain severity following intravitreal injection of bevacizumab (IVB).

Design

Prospective, randomized, four-armed, clinical trial.

Methods

The present study was a prospective, randomized, four-armed clinical trial, which included 1004 eyes from 1004 patients. Patients receiving IVB were randomly assigned into four groups: superotemporal (ST); superonasal (SN); inferotemporal (IT); and inferonasal (IN) injections. The visual analog scale (VAS) was used to assess pain. Primary study variables were the relationship between pain severity and injection site, number of previous injections, age, sex, and indication for injection. Secondary variables included best-corrected visual acuity (BCVA) and central macular

SUBMITTER: Karimi S 

PROVIDER: S-EPMC6367313 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature