Characteristics of Subpatent Malaria in a Pre-Elimination Setting in Southern Zambia.

ABSTRACT: To achieve and sustain malaria elimination, identification and treatment of the asymptomatic infectious reservoir is critical. Malaria rapid diagnostic tests (RDTs) are frequently used to identify asymptomatic, Plasmodium-infected individuals through test-and-treat strategies, but their sensitivity is low when used in low transmission settings. Characteristics of individuals with subpatent (RDT-negative but polymerase chain reaction [PCR]-positive) Plasmodium parasitemia were evaluated in southern Zambia where malaria transmission has declined and efforts to achieve malaria elimination are underway. Simple random sampling based on satellite imagery was used to select households for participation in community-based, cross-sectional surveys between 2008 and 2013. Questionnaires

SUBMITTER: Kobayashi T 

PROVIDER: S-EPMC6367603 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature