Projected impact of a multigene pharmacogenetic test to optimize medication prescribing in cardiovascular patients.

ABSTRACT:

Aim

To determine the projected impact of a multigene pharmacogenetic (PGx) test on medication prescribing.

Materials & methods

A retrospective analysis was conducted with 122 cardiac catheterization laboratory patients undergoing angiography for eligibility of potential PGx-guided interventions that could have occurred if multigene PGx information was pre-emptively available at the time of the procedure. Medication data and presence of actionable at-risk genotypes were used to determine eligibility of a PGx intervention.

Results

20% of the study population (n = 24) would have qualified for at least one PGx-based medication intervention per US FDA or Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines within 6 months of their cardiac catheterization p

SUBMITTER: Dong OM 

PROVIDER: S-EPMC6367721 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature