Clinical course & management of childhood nephrotic syndrome in Germany: a large epidemiological ESPED study.

ABSTRACT: BACKGROUND:Nephrotic syndrome (NS) is one of the most frequent occurring chronic kidney diseases in childhood, despite its rarely occurrence in the general population. Detailed information about clinical data of NS (e.g. average length of stay, complications) as well as of secondary nephrotic syndrome (SNS) is not well known. METHODS:A nationwide ESPED follow-up study presenting the clinical course and management of children with NS in Germany. RESULTS:In course of 2 years, 347 children developed the first onset of NS, hereof 326 patients (93.9%) had a primary NS, and 19 patients had a SNS (missing data in 2 cases), the majority due to a Henoch-Schönlein Purpura. Patients with steroid-resistant NS (SRNS) stayed significantly longer in hospital than children with steroid-sensitive NS (25.2

SUBMITTER: Franke I 

PROVIDER: S-EPMC6367765 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature