Associations of the Mediterranean diet with cognitive and neuroimaging phenotypes of dementia in healthy older adults.

ABSTRACT: Background:Accumulating evidence suggests that higher Mediterranean diet (MedDiet) adherence is associated with higher global cognitive performance and brain structural integrity as well as decreased risk of Alzheimer disease (AD) and vascular dementia (VaD). Objectives:We directly examined cross-sectional associations between the MedDiet and cognitive and neuroimaging phenotypes associated with AD and VaD (separately) in a cohort of nondemented, nondepressed older adults. Methods:Community-dwelling older adults (n = 82; aged ∼68.8 y; 50% female, 50% minority) underwent dietary (Block Food Frequency Questionnaire 2005) and neuropsychological assessments and neuroimaging. MedDiet scores were quantified with the use of published criteria, and participants were divided into High and Low (medi

SUBMITTER: Karstens AJ 

PROVIDER: S-EPMC6367961 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature