Neglected tropical diseases in children: An assessment of gaps in research prioritization.

ABSTRACT:

Background

Despite the known burden of neglected tropical diseases (NTDs) on child health, there is limited information on current efforts to increase pediatric therapeutic options. Our objective was to quantify and characterize research activity and treatment availability for NTDs in children in order to inform the prioritization of future research efforts.

Methodology/principal findings

We conducted a review of the World Health Organization's (WHO) International Clinical Trials Registry Platform to assess research activity for NTDs. The burden of disease of each NTD was measured in terms of disability adjusted life years (DALYs), which was extracted from the Global Health Data Exchange. First- and second-line medications for each NTD were identified from WHO guidelines. We

SUBMITTER: Rees CA 

PROVIDER: S-EPMC6368333 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature