Short-term effects of airport-associated ultrafine particle exposure on lung function and inflammation in adults with asthma.

ABSTRACT:

Background

Exposure to ultrafine particles (UFP, particles with aerodynamic diameter < 100 nm) is associated with reduced lung function and airway inflammation in individuals with asthma. Recently, elevated UFP number concentrations (PN) from aircraft landing and takeoff activity were identified downwind of the Los Angeles International Airport (LAX) but little is known about the health impacts of airport-related UFP exposure.

Methods

We conducted a randomized crossover study of 22 non-smoking adults with mild to moderate asthma in Nov-Dec 2014 and May-Jul 2015 to investigate short-term effects of exposure to LAX airport-related UFPs. Participants conducted scripted, mild walking activity on two occasions in public parks inside (exposure) and outside (control) of the high UF

SUBMITTER: Habre R 

PROVIDER: S-EPMC6368339 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature