Association of Rapid Molecular Testing With Duration of Respiratory Isolation for Patients With Possible Tuberculosis in a US Hospital.

ABSTRACT:

Importance

New guidelines recommend that molecular testing replace sputum-smear microscopy to guide discontinuation of respiratory isolation in patients undergoing evaluation for active tuberculosis (TB) in health care settings.

Objective

To evaluate the implementation and impact of a molecular testing strategy to guide discontinuation of isolation.

Design, setting, and participants

Prospective cohort study with a pragmatic, before-and-after-implementation design of 621 consecutive patients hospitalized at Zuckerberg San Francisco General Hospital and Trauma Center who were undergoing sputum examination for evaluation for active pulmonary TB from January 2014 to January 2016.

Interventions

Implementation of a sputum molecular testing algorithm using GeneXpert M

SUBMITTER: Chaisson LH 

PROVIDER: S-EPMC6368387 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature