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The dynamical signature of anhedonia in major depressive disorder: positive emotion dynamics, reactivity, and recovery.


ABSTRACT:

Background

Major Depressive Disorder (MDD) is the leading cause of disability worldwide. The cardinal features of MDD are depressed mood and anhedonia. Anhedonia is defined as a "markedly diminished interest or pleasure in all, or almost all, activities of the day", and has generally been investigated on group-level using retrospective data (e.g. via questionnaire/interview). However, inferences based on group-level findings not necessarily generalize to daily life experiences within individuals.

Methods

We repeatedly sampled pleasurable experiences within individuals' daily lives by means of Experience Sampling Methods, and compared how positive affect unfolded in the daily life of healthy controls versus patients diagnosed with MDD and anhedonia. We sampled Positive Affect

SUBMITTER: Heininga VE 

PROVIDER: S-EPMC6368777 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature