One-carbon metabolism nutrient intake and the association between body mass index and urinary arsenic metabolites in adults in the Chihuahua cohort.

ABSTRACT:

Background

Exposure to inorganic arsenic (iAs) via drinking water is a serious global health threat. Various factors influence susceptibility to iAs-associated health outcomes, including differences in iAs metabolism. Previous studies have shown that obesity is associated with iAs metabolism. It has been hypothesized that this association can be explained by confounding from nutritional factors involved in one-carbon metabolism, such as folate or other B vitamins, whose intake may differ across BMI categories and is known be associated with iAs metabolism. However, no studies have explored whether this association is confounded by nutritional factors.

Methods

We investigated the relationship between body mass index (BMI) and the distribution of urinary arsenic species in a c

SUBMITTER: Bommarito PA 

PROVIDER: S-EPMC6369528 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature