Bridging antimicrobial resistance knowledge gaps: The East African perspective on a global problem.

ABSTRACT:

Background

There is worldwide concern of rapidly increasing antimicrobial resistance (AMR). However, there is paucity of resistance surveillance data and updated antibiograms in Africa in general. This study was undertaken in Kenyatta National Hospital (KNH) -the largest public tertiary referral centre in East & Central Africa-to help bridge existing AMR knowledge and practice gaps.

Methods

A retrospective review of VITEK 2 (bioMérieux) records capturing antimicrobial susceptibility data for the year 2015 was done and analysed using WHONET and SPSS.

Results

Analysis of 624 isolates revealed AMR rates higher than most recent local and international reports. 88% of isolates tested were multi-drug resistant (MDR) whereas 26% were extensively-drug resistant (XDR). E. coli

SUBMITTER: Wangai FK 

PROVIDER: S-EPMC6370290 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature