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Comparative Study of Immune Reaction Against Bacterial Infection From Transcriptome Analysis.


ABSTRACT: Transcriptome analysis is a powerful tool that enables a deep understanding of complicated physiological pathways, including immune responses. RNA sequencing (RNA-Seq)-based transcriptome analysis and various bioinformatics tools have also been used to study non-model animals, including aquaculture species for which reference genomes are not available. Rapid developments in these techniques have not only accelerated investigations into the process of pathogenic infection and defense strategies in fish, but also used to identify immunity-related genes in fish. These findings will contribute to fish immunotherapy for the prevention and treatment of bacterial infections through the design of more specific and effective immune stimulants, adjuvants, and vaccines. Until now, there has been litt

SUBMITTER: Maekawa S 

PROVIDER: S-EPMC6370674 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature