Impact of physical activity in vascular cognitive impairment (AFIVASC): study protocol for a randomised controlled trial.

ABSTRACT:

Background

Cognitive impairment and cerebrovascular pathology are both frequent with ageing. Cognitive impairment due to vascular pathology of the brain, termed vascular cognitive impairment (VCI), is one of the most frequent causes of cognitive impairment in elderly subjects. Thus far, VCI has no specific pharmacological treatment. Recent observational studies have suggested a protective effect of physical activity in cognition, but adequate randomised controlled trials (RCT) are lacking.

Methods

AFIVASC is a multi-centre randomised controlled trial, with a 6-month intervention treatment and an additional follow-up of 6 months, that aims to estimate the impact of 6 months of moderate intensity physical activity on cognition (the primary outcome) at 6 and 12 months in subjec

SUBMITTER: Verdelho A 

PROVIDER: S-EPMC6371566 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature