Diet during Pregnancy and Infancy and the Infant Intestinal Microbiome.

ABSTRACT:

Objectives

To determine the association between diet during pregnancy and infancy, including breastfeeding vs formula feeding, solid food introduction, and the infant intestinal microbiome.

Study design

Infants participating in the Vitamin D Antenatal Asthma Reduction Trial were included in this study (n = 323). Maternal and infant diets were assessed by questionnaire. Infant stool samples were collected at age 3-6 months. Stool sequencing was performed using the Roche 454 platform. Analyses were stratified by race/ethnicity.

Results

Breastfeeding, compared with formula feeding, was independently associated with infant intestinal microbial diversity. Breastfeeding also had the most consistent associations with individual taxa that have been previously linked to early-

SUBMITTER: Savage JH 

PROVIDER: S-EPMC6371799 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature