An epigenome-wide association study meta-analysis of educational attainment.

ABSTRACT: The epigenome is associated with biological factors, such as disease status, and environmental factors, such as smoking, alcohol consumption and body mass index. Although there is a widespread perception that environmental influences on the epigenome are pervasive and profound, there has been little evidence to date in humans with respect to environmental factors that are biologically distal. Here we provide evidence on the associations between epigenetic modifications-in our case, CpG methylation-and educational attainment (EA), a biologically distal environmental factor that is arguably among the most important life-shaping experiences for individuals. Specifically, we report the results of an epigenome-wide association study meta-analysis of EA based on data from 27 cohort studies with

SUBMITTER: Karlsson Linner R 

PROVIDER: S-EPMC6372242 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature