Whole-Genome Sequences of Five Acinetobacter baumannii Strains From a Child With Leukemia M2.

ABSTRACT: Acinetobacter baumannii is an opportunistic pathogen and is one of the primary etiological agents of healthcare-associated infections (HAIs). A. baumannii infections are difficult to treat due to the intrinsic and acquired antibiotic resistance of strains of this bacterium, which frequently limits therapeutic options. In this study, five A. baumannii strains (810CP, 433H, 434H, 483H, and A-2), all of which were isolated from a child with leukemia M2, were characterized through antibiotic susceptibility profiling, the detection of genes encoding carbapenem hydrolyzing oxacillinases, pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), adherence and invasion assays toward the A549 cell line, and the whole-genome sequence (WGS). The five strains sho

SUBMITTER: Mancilla-Rojano J 

PROVIDER: S-EPMC6372515 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature