Ontology highlight
ABSTRACT:
SUBMITTER: Spitzer SO
PROVIDER: S-EPMC6372724 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Spitzer Sonia Olivia SO Sitnikov Sergey S Kamen Yasmine Y Evans Kimberley Anne KA Kronenberg-Versteeg Deborah D Dietmann Sabine S de Faria Omar O Agathou Sylvia S Káradóttir Ragnhildur Thóra RT
Neuron 20190114 3
Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating oligodendrocytes during CNS development, are the main proliferative cells in the adult brain. OPCs are conventionally considered a homogeneous population, particularly with respect to their electrophysiological properties, but this has been debated. We show, by using single-cell electrophysiological recordings, that OPCs start out as a homogeneous population but become functionally heterogeneous, varying both within an ...[more]