Maternal hepatitis B surface antigen carrier status increased the incidence of gestational diabetes mellitus.

ABSTRACT:

Background

The relationship between chronic hepatitis B virus (HBV) infection with gestational diabetes mellitus (GDM) remains unclear. This study aimed to identify the association between maternal HBsAg-positive status and GDM.

Methods

A retrospective cohort study was performed on the pregnant women who delivered from June 2012 to May 2016 at Wuhan Medical Care Center for Women and Children, Wuhan, China. We compared the incidence of GDM between HBsAg-positive pregnant women and HBsAg-negative controls. A multivariate regression model was used to measure the independent association between maternal HBsAg carrier and the risk of developing GDM.

Results

In total, 964 HBsAg-positive pregnant women and 964 HBsAg-negative women were included into the study. We observed ma

SUBMITTER: Peng S 

PROVIDER: S-EPMC6373004 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature